DegronMD

Uniprot ID: Q14118

Source protein: Dystroglycan 1

Source gene: DAG1

Class: LIG_APCC_ABBA_1

Location: 154:159

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.9302

ASA_SCORE: 47.0333

COIL: 0.3522

CONS_SCORE: 0.5283

DSS_SCORE: 0.4466

HELIX: 0.0275

FCONS_SCORE: 1.2949

RIG_SCORE: 0.7549

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Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.S166L	TCGA-HF-7132	STAD	TCGA	IEVYPE	LIG_APCC_ABBA_1	0.1389
p.S166L	TCGA-HU-A4G8	STAD	TCGA	IEVYPE	LIG_APCC_ABBA_1	0.1389
p.S166L	DO47819	STAD	ICGC	IEVYPE	LIG_APCC_ABBA_1	0.1389
p.S166L	DO38214	STAD	ICGC	IEVYPE	LIG_APCC_ABBA_1	0.1389

Showing 1 to 4 of 4 entries

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Sample	Cancer	Mutation (In Degron?)	Dataset	Drug	IC50
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Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q14118	Dystroglycan 1	LIG_APCC_ABBA_1	154:159	IEVYPE	APC,CDC20,FZR1	0.9302	More...

Showing 1 to 1 of 1 entries

DegronMD: protein-targeted degradation, mutation and drug response to degrons