DegronMD

Uniprot ID: O95125

Source protein: Zinc finger protein 202

Source gene: ZNF202

Class: DEG_SCF_FBW7_2

Location: 348:355

E3 ligase: FBXW7

DEGRON score: 0.704

ASA_SCORE: 82.0125

COIL: 0.6321

CONS_SCORE: 0.6296

DSS_SCORE: 0.4825

HELIX: 0.1065

FCONS_SCORE: 0.9991

RIG_SCORE: 0.7677

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.D360N	TCGA-05-4250	LUAD	TCGA	IHQTPDWE	DEG_SCF_FBW7_2	0.1944
p.D360N	DO24457	LUAD	ICGC	IHQTPDWE	DEG_SCF_FBW7_2	0.1944
p.P352T	TCGA-A5-A0G2	UCEC	TCGA	IHQTPDWE	DEG_SCF_FBW7_2	0.7031
p.P352T	DO41235	UCEC	ICGC	IHQTPDWE	DEG_SCF_FBW7_2	0.7031
p.G363C	TCGA-B5-A0JR	UCEC	TCGA	IHQTPDWE	DEG_SCF_FBW7_2	0.1111
p.G363C	DO41791	UCEC	ICGC	IHQTPDWE	DEG_SCF_FBW7_2	0.1111
p.E359K	TCGA-FD-A3SS	BLCA	TCGA	IHQTPDWE	DEG_SCF_FBW7_2	0.2222
p.E359K	DO737	BLCA	ICGC	IHQTPDWE	DEG_SCF_FBW7_2	0.2222
p.H349Y	DO48413	BLCA	ICGC	IHQTPDWE	DEG_SCF_FBW7_2	0.6118

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
O95125	Zinc finger protein 202	DEG_SCF_FBW7_2	348:355	IHQTPDWE	FBXW7	0.704	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons