DegronMD

Uniprot ID: Q96RL7

Source protein: Intermembrane lipid transfer protein VPS13A

Source gene: VPS13A

Class: LIG_APCC_ABBA_1

Location: 2498:2503

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.5436

ASA_SCORE: 21.4333

COIL: 0.2225

CONS_SCORE: 0.386

DSS_SCORE: 0.0379

HELIX: 0.0077

FCONS_SCORE: 1.275

RIG_SCORE: 0.9324

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.R2506S	DO35083	PACA	ICGC	IILFTE	LIG_APCC_ABBA_1	0.25

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q96RL7	Intermembrane lipid transfer protein VPS13A	LIG_APCC_ABBA_1	2498:2503	IILFTE	APC,CDC20,FZR1	0.5436	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons