DegronMD

Uniprot ID: Q7Z2Z2

Source protein: Elongation factor-like GTPase 1

Source gene: EFL1

Class: LIG_APCC_ABBA_1

Location: 689:694

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.9441

ASA_SCORE: 43.1667

COIL: 0.2368

CONS_SCORE: 0.8122

DSS_SCORE: 0.3333

HELIX: 0.0368

FCONS_SCORE: 1.5165

RIG_SCORE: 0.7949

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.E687K	SIDM00114	Non-Small Cell Lung Carcinoma	GDSC	IIPFRE	LIG_APCC_ABBA_1	0.2778
p.E687K	H513	pleura	COSMIC	IIPFRE	LIG_APCC_ABBA_1	0.2778

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q7Z2Z2	Elongation factor-like GTPase 1	LIG_APCC_ABBA_1	689:694	IIPFRE	APC,CDC20,FZR1	0.9441	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons