DegronMD

Uniprot ID: Q6ZUX3

Source protein: TOG array regulator of axonemal microtubules protein 2

Source gene: TOGARAM2

Class: DEG_SCF_FBW7_1

Location: 181:188

E3 ligase: FBXW7

DEGRON score: 0.9691

ASA_SCORE: 84.8125

COIL: 0.9221

CONS_SCORE: 0.3697

DSS_SCORE: 0.6175

HELIX: 0.0414

FCONS_SCORE: 0.9523

RIG_SCORE: 0.6558

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.P198S	SIDM00254	Neuroblastoma	GDSC	IPTTPEAS	DEG_SCF_FBW7_1	0.0556

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q6ZUX3	TOG array regulator of axonemal microtubules protein 2	DEG_SCF_FBW7_1	181:188	IPTTPEAS	FBXW7	0.9691	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons