DegronMD

Uniprot ID: A2AJT9

Source protein: BCLAF1 and THRAP3 family member 3

Source gene: BCLAF3

Class: DEG_APCC_DBOX_1

Location: 83:91

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.854

ASA_SCORE: 93.7444

COIL: 0.7626

CONS_SCORE: 0.5662

DSS_SCORE: 0.5038

HELIX: 0.2257

FCONS_SCORE: 0.8086

RIG_SCORE: 0.7164

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.P95S	SIDM00121	T-Lymphoblastic Leukemia	GDSC	IRNSLENVY	DEG_APCC_DBOX_1	0.2222
p.P95S	CCRF-CEM	haematopoietic_and_lymphoid_tissue	COSMIC	IRNSLENVY	DEG_APCC_DBOX_1	0.2222
p.P79T	SIDM00673	Breast Carcinoma	GDSC	IRNSLENVY	DEG_APCC_DBOX_1	0.2222

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
A2AJT9	BCLAF1 and THRAP3 family member 3	DEG_APCC_DBOX_1	83:91	IRNSLENVY	APC,CDC20,FZR1	0.854	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons