DegronMD - A2AJT9(BCLAF3)

GO - Biological processes (BP): View more >>

GO - Molecular function (MF): View more >>

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D252V	SIDM00285	Neuroblastoma	GDSC	LPPYQE	LIG_APCC_ABBA_1	244:249	Mutation rewiring degron network	0.25
p.D252V	CHP-134	autonomic ganglia	COSMIC	LPPYQE	LIG_APCC_ABBA_1	244:249	Mutation rewiring degron network	0.25
p.P95S	SIDM00121	T-Lymphoblastic Leukemia	GDSC	IRNSLENVY	DEG_APCC_DBOX_1	83:91	Mutation rewiring degron network	0.2222
p.P95S	CCRF-CEM	haematopoietic and lymphoid tissue	COSMIC	IRNSLENVY	DEG_APCC_DBOX_1	83:91	Mutation rewiring degron network	0.2222
p.P79T	SIDM00673	Breast Carcinoma	GDSC	IRNSLENVY	DEG_APCC_DBOX_1	83:91	Mutation rewiring degron network	0.2222

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons