DegronMD

Uniprot ID: Q9BY89

Source protein: Uncharacterized protein KIAA1671

Source gene: KIAA1671

Class: LIG_APCC_ABBA_1

Location: 441:446

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.6595

ASA_SCORE: 97.0667

COIL: 0.469

CONS_SCORE: 0.589

DSS_SCORE: 0.2196

HELIX: 0.4727

FCONS_SCORE: 1.5333

RIG_SCORE: 0.8298

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.G455V	DO229034	LICA	ICGC	ISLFRE	LIG_APCC_ABBA_1	0.0833
p.K439R	DO229047	LICA	ICGC	ISLFRE	LIG_APCC_ABBA_1	0.2778
p.R445Q	SIDM00936	Bladder Carcinoma	GDSC	ISLFRE	LIG_APCC_ABBA_1	0.6218
p.R445Q	CAL-29	urinary_tract	COSMIC	ISLFRE	LIG_APCC_ABBA_1	0.6218

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9BY89	Uncharacterized protein KIAA1671	LIG_APCC_ABBA_1	441:446	ISLFRE	APC,CDC20,FZR1	0.6595	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons