DegronMD

Uniprot ID: Q02505

Source protein: Mucin-3A

Source gene: MUC3A

Class: DEG_SCF_FBW7_1

Location: 2405:2410

E3 ligase: FBXW7

DEGRON score: 0.9532

ASA_SCORE: 89.6333

COIL: 0.9228

CONS_SCORE: 0.6385

DSS_SCORE: 0.537

HELIX: 0.0108

FCONS_SCORE: 0.8842

RIG_SCORE: 0.7229

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Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.T2399A	SIDM01126	Small Cell Lung Carcinoma	GDSC	ITPGLT	DEG_SCF_FBW7_1	0.1667
p.T2399A	SIDM00846	Cervical Carcinoma	GDSC	ITPGLT	DEG_SCF_FBW7_1	0.1667
p.T2399A	SIDM00633	Breast Carcinoma	GDSC	ITPGLT	DEG_SCF_FBW7_1	0.1667
p.T2399A	SIDM01099	Neuroblastoma	GDSC	ITPGLT	DEG_SCF_FBW7_1	0.1667

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Sample	Cancer	Mutation (In Degron?)	Dataset	Drug	IC50
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Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q02505	Mucin-3A	DEG_SCF_FBW7_1	2405:2410	ITPGLT	FBXW7	0.9532	More...

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DegronMD: protein-targeted degradation, mutation and drug response to degrons