DegronMD

Uniprot ID: Q96M83

Source protein: Coiled-coil domain-containing protein 7

Source gene: CCDC7

Class: DEG_SCF_FBW7_2

Location: 881:886

E3 ligase: FBXW7

DEGRON score: 0.7996

ASA_SCORE: 100.95

COIL: 0.9005

CONS_SCORE: 0

DSS_SCORE: 0.6572

HELIX: 0.0623

FCONS_SCORE: 0

RIG_SCORE: 0.6955

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.N889S	SIDM01024	Esophageal Squamous Cell Carcinoma	GDSC	ITPGRE	DEG_SCF_FBW7_2	0.25
p.N889S	KYSE-70	oesophagus	COSMIC	ITPGRE	DEG_SCF_FBW7_2	0.25

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q96M83	Coiled-coil domain-containing protein 7	DEG_SCF_FBW7_2	881:886	ITPGRE	FBXW7	0.7996	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons