DegronMD

Uniprot ID: Q8IWY9

Source protein: Codanin-1

Source gene: CDAN1

Class: DEG_SCF_FBW7_1

Location: 827:832

E3 ligase: FBXW7

DEGRON score: 0.5439

ASA_SCORE: 53.7167

COIL: 0.5055

CONS_SCORE: 0.6714

DSS_SCORE: 0.5583

HELIX: 0.0142

FCONS_SCORE: 1.4938

RIG_SCORE: 0.7428

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.R825K	DO227854	BRCA	ICGC	ITPTTT	DEG_SCF_FBW7_1	0.2778
p.Q841K	DO233835	GACA	ICGC	ITPTTT	DEG_SCF_FBW7_1	0.0833
p.R819Q	DO27839	MALY	ICGC	ITPTTT	DEG_SCF_FBW7_1	0.1111

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q8IWY9	Codanin-1	DEG_SCF_FBW7_1	827:832	ITPTTT	FBXW7	0.5439	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons