DegronMD - Q8IWY9(CDAN1)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.T191M	TCGA-32-2616	GBM	TCGA	INPTPVSE	DEG_SCF_FBW7_2	197:204	Mutation rewiring degron network	0.1667
p.T191M	DO233179	GACA	ICGC	INPTPVSE	DEG_SCF_FBW7_2	197:204	Mutation rewiring degron network	0.1667
p.T191M	DO13462	GBM	ICGC	INPTPVSE	DEG_SCF_FBW7_2	197:204	Mutation rewiring degron network	0.1667
p.R195H	TCGA-AG-A002	READ	TCGA	INPTPVSE	DEG_SCF_FBW7_2	197:204	Mutation rewiring degron network	0.2778
p.P201T	TCGA-AJ-A23O	UCEC	TCGA	INPTPVSE	DEG_SCF_FBW7_2	197:204	Mutation altering degron motif	0.7031
p.P201T	DO43290	UCEC	ICGC	INPTPVSE	DEG_SCF_FBW7_2	197:204	Mutation altering degron motif	0.7031
p.E205K	TCGA-B5-A0K1	UCEC	TCGA	INPTPVSE	DEG_SCF_FBW7_2	197:204	Mutation rewiring degron network	0.3056
p.E205K	DO41839	UCEC	ICGC	INPTPVSE	DEG_SCF_FBW7_2	197:204	Mutation rewiring degron network	0.3056
p.R196M	TCGA-CG-4306	STAD	TCGA	INPTPVSE	DEG_SCF_FBW7_2	197:204	Mutation rewiring degron network	0.3056
p.R196M	DO38567	STAD	ICGC	INPTPVSE	DEG_SCF_FBW7_2	197:204	Mutation rewiring degron network	0.3056
p.R206Q	TCGA-HU-A4GT	STAD	TCGA	INPTPVSE	DEG_SCF_FBW7_2	197:204	Mutation rewiring degron network	0.2778
p.R206Q	DO48020	STAD	ICGC	INPTPVSE	DEG_SCF_FBW7_2	197:204	Mutation rewiring degron network	0.2778
p.R825K	DO227854	BRCA	ICGC	ITPTTT	DEG_SCF_FBW7_1	827:832	Mutation rewiring degron network	0.2778
p.Q841K	DO233835	GACA	ICGC	ITPTTT	DEG_SCF_FBW7_1	827:832	Mutation rewiring degron network	0.0833
p.P69H	DO229018	LICA	ICGC	PPTPAKT	DEG_SCF_FBW7_1	69:75	Mutation altering degron motif	0.7694
p.R819Q	DO27839	MALY	ICGC	ITPTTT	DEG_SCF_FBW7_1	827:832	Mutation rewiring degron network	0.1111
p.G190W	DO35442	PACA	ICGC	INPTPVSE	DEG_SCF_FBW7_2	197:204	Mutation rewiring degron network	0.1389
p.K212N	DO232761	PBCA	ICGC	INPTPVSE	DEG_SCF_FBW7_2	197:204	Mutation substituting flanking lysine	0.2222
p.K210N	DO232224	PBCA	ICGC	INPTPVSE	DEG_SCF_FBW7_2	197:204	Mutation substituting flanking lysine	0.2778
p.Q67R	DO218908	SKCA	ICGC	PPTPAKT	DEG_SCF_FBW7_1	69:75	Mutation rewiring degron network	0.2778
p.T71P	DO218854	SKCA	ICGC	PPTPAKT	DEG_SCF_FBW7_1	69:75	Mutation altering degron motif	0.8142
p.L208I	SIDM01007	T-Lymphoblastic Leukemia	GDSC	INPTPVSE	DEG_SCF_FBW7_2	197:204	Mutation rewiring degron network	0.2222
p.L208I	ACH-002256	Leukemia	CCLE	INPTPVSE	DEG_SCF_FBW7_2	197:204	Mutation rewiring degron network	0.2222
p.L208I	KARPAS-45	haematopoietic and lymphoid tissue	COSMIC	INPTPVSE	DEG_SCF_FBW7_2	197:204	Mutation rewiring degron network	0.2222
p.S194P	SIDM00660	Colorectal Carcinoma	GDSC	INPTPVSE	DEG_SCF_FBW7_2	197:204	Mutation rewiring degron network	0.25
p.S194P	ACH-000985	Colon/Colorectal Cancer	CCLE	INPTPVSE	DEG_SCF_FBW7_2	197:204	Mutation rewiring degron network	0.25
p.S194P	LS-411N	large intestine	COSMIC	INPTPVSE	DEG_SCF_FBW7_2	197:204	Mutation rewiring degron network	0.25

Kaplan plot for CDAN1 in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

CDAN1

UniProt ID: Q8IWY9

Entrez ID: 146059

Protein name: Codanin-1

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for CDAN1 in