DegronMD

Uniprot ID: Q02505

Source protein: Mucin-3A

Source gene: MUC3A

Class: DEG_SCF_FBW7_1

Location: 1140:1147

E3 ligase: FBXW7

DEGRON score: 0.9675

ASA_SCORE: 97.05

COIL: 0.9163

CONS_SCORE: 0.4534

DSS_SCORE: 0.5353

HELIX: 0.0106

FCONS_SCORE: 1

RIG_SCORE: 0.7821

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.P1144H	SIDM00114	Non-Small Cell Lung Carcinoma	GDSC	ITTTPNTT	DEG_SCF_FBW7_1	0.7694
p.T1143A	SIDM00118	Colorectal Carcinoma	GDSC	ITTTPNTT	DEG_SCF_FBW7_1	0.7139

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q02505	Mucin-3A	DEG_SCF_FBW7_1	1140:1147	ITTTPNTT	FBXW7	0.9675	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons