DegronMD

Uniprot ID: Q9H0U4

Source protein: Ras-related protein Rab-1B

Source gene: RAB1B

Class: DEG_SCF_SKP2-CKS1_1

Location: 187:194

E3 ligase: SKP2,CSK1

DEGRON score: 0.9943

ASA_SCORE: 102.8

COIL: 0.9366

CONS_SCORE: 0.4188

DSS_SCORE: 0.5862

HELIX: 0.0179

FCONS_SCORE: 0.957

RIG_SCORE: 0.7026

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.C200S	TCGA-58-8388	LUSC	TCGA	KIDSTPVK	DEG_SCF_SKP2-CKS1_1	0.1667
p.E182K	TCGA-C5-A901	CESC	TCGA	KIDSTPVK	DEG_SCF_SKP2-CKS1_1	0.1944
p.R183W	TCGA-UD-AAC1	MESO	TCGA	KIDSTPVK	DEG_SCF_SKP2-CKS1_1	0.2222

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9H0U4	Ras-related protein Rab-1B	DEG_SCF_SKP2-CKS1_1	187:194	KIDSTPVK	SKP2,CSK1	0.9943	More...
Q92928	Putative Ras-related protein Rab-1C	DEG_SCF_SKP2-CKS1_1	187:194	KIDSTPVK	SKP2,CSK1	0.9794	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons