DegronMD

Uniprot ID: Q8WY41

Source protein: Nanos homolog 1

Source gene: NANOS1

Class: DEG_APCC_TPR_1

Location: 290:292

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.9974

ASA_SCORE: 152.8333

COIL: 0.9387

CONS_SCORE: 0.3604

DSS_SCORE: 0.9935

HELIX: 0.0223

FCONS_SCORE: 1.2256

RIG_SCORE: 0.6432

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.R280H	ACH-000941	Endometrial/Uterine Cancer	CCLE	KLR	DEG_APCC_TPR_1	0.0556

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q8WY41	Nanos homolog 1	DEG_APCC_TPR_1	290:292	KLR	APC,CDC20,FZR1	0.9974	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons