DegronMD

Uniprot ID: Q9C0D2

Source protein: Centrosomal protein of 295 kDa

Source gene: CEP295

Class: LIG_APCC_ABBAyCdc20_2

Location: 1867:1873

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.827

ASA_SCORE: 95.4286

COIL: 0.8777

CONS_SCORE: 0.3889

DSS_SCORE: 0.3734

HELIX: 0.0389

FCONS_SCORE: 0.8226

RIG_SCORE: 0.736

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Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
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Sample	Cancer	Mutation (In Degron?)	Dataset	Drug	IC50
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Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9C0D2	Centrosomal protein of 295 kDa	LIG_APCC_ABBAyCdc20_2	1867:1873	KPGIYED	APC,CDC20,FZR1	0.827	More...

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DegronMD: protein-targeted degradation, mutation and drug response to degrons