DegronMD - Q9C0D2(CEP295)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.L1096M	SIDM00885	Breast Carcinoma	GDSC	VSSSS	DEG_SPOP_SBC_1	1097:1101	Mutation rewiring degron network	0.3056
p.L1096M	HCC1187	breast	COSMIC	VSSSS	DEG_SPOP_SBC_1	1097:1101	Mutation rewiring degron network	0.3056
p.P1120R	SIDM01145	Gastric Carcinoma	GDSC	EKENV	DEG_APCC_KENBOX_2	1130:1134	Mutation rewiring degron network	0.0556
p.P1120R	NCI-SNU-16	stomach	COSMIC	EKENV	DEG_APCC_KENBOX_2	1130:1134	Mutation rewiring degron network	0.0556
p.S1560Y	SIDM00249	Esophageal Squamous Cell Carcinoma	GDSC	VCSSS	DEG_SPOP_SBC_1	1546:1550	Mutation rewiring degron network	0.0556
p.S1560Y	TE-15	oesophagus	COSMIC	VCSSS	DEG_SPOP_SBC_1	1546:1550	Mutation rewiring degron network	0.0556
p.S2091P	SIDM00986	Head and Neck Carcinoma	GDSC	LEPHPD	LIG_APCC_ABBA_1	2082:2087	Mutation rewiring degron network	0.2222

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons