DegronMD

Uniprot ID: Q9H2K0

Source protein: Translation initiation factor IF-3, mitochondrial

Source gene: MTIF3

Class: DEG_APCC_DBOX_1

Location: 7:15

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.7048

ASA_SCORE: 68.8222

COIL: 0.1832

CONS_SCORE: 0.4794

DSS_SCORE: 0.0927

HELIX: 0.7671

FCONS_SCORE: 1.2865

RIG_SCORE: 0.8668

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.G25C	TCGA-66-2766	LUSC	TCGA	KRLTLQTVK	DEG_APCC_DBOX_1	0.0556
p.G25C	DO27747	LUSC	ICGC	KRLTLQTVK	DEG_APCC_DBOX_1	0.0556
p.S16F	TCGA-FD-A6TA	BLCA	TCGA	KRLTLQTVK	DEG_APCC_DBOX_1	0.3056
p.S16F	DO49753	BLCA	ICGC	KRLTLQTVK	DEG_APCC_DBOX_1	0.3056

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9H2K0	Translation initiation factor IF-3, mitochondrial	DEG_APCC_DBOX_1	7:15	KRLTLQTVK	APC,CDC20,FZR1	0.7048	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons