DegronMD: protein-targeted degradation, mutation and drug response to degrons
Home
(current)
Browse
Proteins/Degrons
Mutations
Drug response
Network-rewiring
Drug resistance
Search
Tutorial
Download
Contact
Links
BSML
CPH
CGC
Degron:
KSVMHPE
Uniprot ID:
Q8NDH2
Source protein:
Leucine-rich repeat transmembrane protein CCDC168
Source gene:
CCDC168
Class:
LIG_APCC_ABBAyCdc20_2
Location:
4643:4649
E3 ligase:
APC,CDC20,FZR1
DEGRON score:
0.7285
ASA_SCORE:
96.5714
COIL:
0.7441
CONS_SCORE:
0
DSS_SCORE:
0.3636
HELIX:
0.1446
FCONS_SCORE:
0
RIG_SCORE:
0.7472
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with CCDC168 mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of KSVMHPE
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q8NDH2
Leucine-rich repeat transmembrane protein CCDC168
LIG_APCC_ABBAyCdc20_2
4643:4649
KSVMHPE
APC,CDC20,FZR1
0.7285
More...