DegronMD

Uniprot ID: Q5QGS0

Source protein: Neurite extension and migration factor

Source gene: NEXMIF

Class: DEG_SCF_FBW7_1

Location: 1370:1377

E3 ligase: FBXW7

DEGRON score: 0.9095

ASA_SCORE: 55.45

COIL: 0.645

CONS_SCORE: 0.7886

DSS_SCORE: 0.5151

HELIX: 0.1551

FCONS_SCORE: 1.0724

RIG_SCORE: 0.7154

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.S1377Y	KARPAS-299	haematopoietic_and_lymphoid_tissue	COSMIC	LAGTPQES	DEG_SCF_FBW7_1	0.712

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q5QGS0	Neurite extension and migration factor	DEG_SCF_FBW7_1	1370:1377	LAGTPQES	FBXW7	0.9095	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons