DegronMD

Uniprot ID: A6H8Y1

Source protein: Transcription factor TFIIIB component B'' homolog

Source gene: BDP1

Class: DEG_ODPH_VHL_1

Location: 1892:1904

E3 ligase: VHL

DEGRON score: 0.8168

ASA_SCORE: 88.0462

COIL: 0.6775

CONS_SCORE: 0.5932

DSS_SCORE: 0.4542

HELIX: 0.2392

FCONS_SCORE: 1.0595

RIG_SCORE: 0.7289

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.E1895K	TCGA-06-5416	GBM	TCGA	LAPEEVNKAPVFV	DEG_ODPH_VHL_1	0.591
p.E1912A	TCGA-BR-4191	STAD	TCGA	LAPEEVNKAPVFV	DEG_ODPH_VHL_1	0.1111
p.D1884G	SIDM01775	B-Cell Non-Hodgkin's Lymphoma	GDSC	LAPEEVNKAPVFV	DEG_ODPH_VHL_1	0.1111

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
A6H8Y1	Transcription factor TFIIIB component B'' homolog	DEG_ODPH_VHL_1	1892:1904	LAPEEVNKAPVFV	VHL	0.8168	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons