DegronMD

Uniprot ID: O15027

Source protein: Protein transport protein Sec16A

Source gene: SEC16A

Class: DEG_ODPH_VHL_1

Location: 2218:2229

E3 ligase: VHL

DEGRON score: 0.7753

ASA_SCORE: 83.1167

COIL: 0.9058

CONS_SCORE: 0

DSS_SCORE: 0.452

HELIX: 0.0475

FCONS_SCORE: 0

RIG_SCORE: 0.7057

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.A2219T	TCGA-D1-A17Q	UCEC	TCGA	LAPLPIPSNLFV	DEG_ODPH_VHL_1	0.7139
p.A2219T	SIDM00537	Colorectal Carcinoma	GDSC	LAPLPIPSNLFV	DEG_ODPH_VHL_1	0.7139
p.N2226D	SIDM00138	Non-Small Cell Lung Carcinoma	GDSC	LAPLPIPSNLFV	DEG_ODPH_VHL_1	0.5821

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
O15027	Protein transport protein Sec16A	DEG_ODPH_VHL_1	2218:2229	LAPLPIPSNLFV	VHL	0.7753	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons