DegronMD

Uniprot ID: Q8TF68

Source protein: Zinc finger protein 384

Source gene: ZNF384

Class: DEG_ODPH_VHL_1

Location: 44:55

E3 ligase: VHL

DEGRON score: 0.9255

ASA_SCORE: 59.5167

COIL: 0.6612

CONS_SCORE: 0.5365

DSS_SCORE: 0.359

HELIX: 0.0154

FCONS_SCORE: 1.2499

RIG_SCORE: 0.7395

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.G64V	TCGA-13-0910	OV	TCGA	LAPPHYPTLLTV	DEG_ODPH_VHL_1	0.0833
p.G64V	TCGA-17-Z042	LUAD	TCGA	LAPPHYPTLLTV	DEG_ODPH_VHL_1	0.0833
p.G64V	DO29186	OV	ICGC	LAPPHYPTLLTV	DEG_ODPH_VHL_1	0.0833
p.P47L	SIDM00658	Non-Small Cell Lung Carcinoma	GDSC	LAPPHYPTLLTV	DEG_ODPH_VHL_1	0.6471
p.P47L	ACH-000852	Lung Cancer	CCLE	LAPPHYPTLLTV	DEG_ODPH_VHL_1	0.6471
p.P47L	NCI-H1435	lung	COSMIC	LAPPHYPTLLTV	DEG_ODPH_VHL_1	0.6471
p.S58P	ACH-000903	Thyroid Cancer	CCLE	LAPPHYPTLLTV	DEG_ODPH_VHL_1	0.25

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q8TF68	Zinc finger protein 384	DEG_ODPH_VHL_1	44:55	LAPPHYPTLLTV	VHL	0.9255	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons