DegronMD

Uniprot ID: Q99684

Source protein: Zinc finger protein Gfi-1

Source gene: GFI1

Class: LIG_APCC_ABBA_1

Location: 151:156

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.9507

ASA_SCORE: 77.75

COIL: 0.7935

CONS_SCORE: 0.4258

DSS_SCORE: 0.3398

HELIX: 0.0975

FCONS_SCORE: 0.8694

RIG_SCORE: 0.7594

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.A149T	DO42673	UCEC	ICGC	LGLFCE	LIG_APCC_ABBA_1	0.2778
p.A149T	SIDM01051	Ovarian Carcinoma	GDSC	LGLFCE	LIG_APCC_ABBA_1	0.2778
p.A149T	ACH-000936	Ovarian Cancer	CCLE	LGLFCE	LIG_APCC_ABBA_1	0.2778

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q99684	Zinc finger protein Gfi-1	LIG_APCC_ABBA_1	151:156	LGLFCE	APC,CDC20,FZR1	0.9507	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons