DegronMD: protein-targeted degradation, mutation and drug response to degrons
Home
(current)
Browse
Proteins/Degrons
Mutations
Drug response
Network-rewiring
Drug resistance
Search
Tutorial
Download
Contact
Links
BSML
CPH
CGC
Degron:
LGTPANS
Uniprot ID:
Q8NDH2
Source protein:
Leucine-rich repeat transmembrane protein CCDC168
Source gene:
CCDC168
Class:
DEG_SCF_FBW7_1
Location:
5745:5751
E3 ligase:
FBXW7
DEGRON score:
0.9709
ASA_SCORE:
70.1571
COIL:
0.7447
CONS_SCORE:
0
DSS_SCORE:
0.2648
HELIX:
0.0617
FCONS_SCORE:
0
RIG_SCORE:
0.7095
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with CCDC168 mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of LGTPANS
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q8NDH2
Leucine-rich repeat transmembrane protein CCDC168
DEG_SCF_FBW7_1
5745:5751
LGTPANS
FBXW7
0.9709
More...