DegronMD

Uniprot ID: Q08E93

Source protein: Protein FAM27E3

Source gene: FAM27E3

Class: DEG_SCF_FBW7_2

Location: 19:25

E3 ligase: FBXW7

DEGRON score: 0.7016

ASA_SCORE: 97.6143

COIL: 0.9133

CONS_SCORE: 0

DSS_SCORE: 0.8092

HELIX: 0.0251

FCONS_SCORE: 0

RIG_SCORE: 0.6358

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.R27C	DO225345	BRCA	ICGC	LHTPKAE	DEG_SCF_FBW7_2	0.2778
p.R27C	DO218863	SKCA	ICGC	LHTPKAE	DEG_SCF_FBW7_2	0.2778
p.T33I	DO229353	LAML	ICGC	LHTPKAE	DEG_SCF_FBW7_2	0.1111
p.R11S	DO232519	PBCA	ICGC	LHTPKAE	DEG_SCF_FBW7_2	0.1111

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q08E93	Protein FAM27E3	DEG_SCF_FBW7_2	19:25	LHTPKAE	FBXW7	0.7016	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons