DegronMD

Uniprot ID: Q9H3T3

Source protein: Semaphorin-6B

Source gene: SEMA6B

Class: DEG_SCF_FBW7_1

Location: 706:713

E3 ligase: FBXW7

DEGRON score: 0.9992

ASA_SCORE: 74.8625

COIL: 0.933

CONS_SCORE: 0.438

DSS_SCORE: 0.7591

HELIX: 0.0286

FCONS_SCORE: 1.1838

RIG_SCORE: 0.624

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.R719H	DO232224	PBCA	ICGC	LLPTPEQT	DEG_SCF_FBW7_1	0.1667

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9H3T3	Semaphorin-6B	DEG_SCF_FBW7_1	706:713	LLPTPEQT	FBXW7	0.9992	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons