DegronMD

Uniprot ID: Q96LU7

Source protein: Myelin regulatory factor-like protein

Source gene: MYRFL

Class: DEG_SCF_FBW7_1

Location: 50:57

E3 ligase: FBXW7

DEGRON score: 0.9949

ASA_SCORE: 81.5875

COIL: 0.9584

CONS_SCORE: 0.3461

DSS_SCORE: 0.5709

HELIX: 0.0244

FCONS_SCORE: 0.963

RIG_SCORE: 0.6616

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.D42G	DO231949	LICA	ICGC	LPDTPPYS	DEG_SCF_FBW7_1	0.1111
p.D42Y	DO229037	LICA	ICGC	LPDTPPYS	DEG_SCF_FBW7_1	0.1111
p.P41L	DO220886	MELA	ICGC	LPDTPPYS	DEG_SCF_FBW7_1	0.0833
p.V61I	A101D	skin	COSMIC	LPDTPPYS	DEG_SCF_FBW7_1	0.2222

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q96LU7	Myelin regulatory factor-like protein	DEG_SCF_FBW7_1	50:57	LPDTPPYS	FBXW7	0.9949	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons