DegronMD

Uniprot ID: Q6PEX7

Source protein: Testis-expressed protein 38

Source gene: TEX38

Class: LIG_APCC_ABBA_1

Location: 147:152

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.8955

ASA_SCORE: 69.7

COIL: 0.7035

CONS_SCORE: 0.9342

DSS_SCORE: 0.3063

HELIX: 0.2017

FCONS_SCORE: 1.2052

RIG_SCORE: 0.7624

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.L162I	TCGA-AA-A010	COAD	TCGA	LPIFQE	LIG_APCC_ABBA_1	0.0556
p.I149N	TCGA-AP-A059	UCEC	TCGA	LPIFQE	LIG_APCC_ABBA_1	0.728
p.P157T	SIDM00596	Endometrial Carcinoma	GDSC	LPIFQE	LIG_APCC_ABBA_1	0.1944
p.P157T	ACH-001517	Endometrial/Uterine Cancer	CCLE	LPIFQE	LIG_APCC_ABBA_1	0.1944
p.P157T	HEC-1	endometrium	COSMIC	LPIFQE	LIG_APCC_ABBA_1	0.1944

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q6PEX7	Testis-expressed protein 38	LIG_APCC_ABBA_1	147:152	LPIFQE	APC,CDC20,FZR1	0.8955	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons