DegronMD

Uniprot ID: Q6AHZ1

Source protein: Zinc finger protein 518A

Source gene: ZNF518A

Class: LIG_APCC_ABBA_1

Location: 809:814

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.9815

ASA_SCORE: 76.8333

COIL: 0.829

CONS_SCORE: 0.4261

DSS_SCORE: 0.6341

HELIX: 0.1045

FCONS_SCORE: 0.9345

RIG_SCORE: 0.7233

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.L811R	SIDM00134	Non-Small Cell Lung Carcinoma	GDSC	LPLHCD	LIG_APCC_ABBA_1	0.8428
p.L811R	HOP-92	lung	COSMIC	LPLHCD	LIG_APCC_ABBA_1	0.8428

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q6AHZ1	Zinc finger protein 518A	LIG_APCC_ABBA_1	809:814	LPLHCD	APC,CDC20,FZR1	0.9815	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons