DegronMD - Q6AHZ1(ZNF518A)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.L811R	SIDM00134	Non-Small Cell Lung Carcinoma	GDSC	LPLHCD	LIG_APCC_ABBA_1	809:814	Mutation altering degron motif	0.8428
p.L811R	HOP-92	lung	COSMIC	LPLHCD	LIG_APCC_ABBA_1	809:814	Mutation altering degron motif	0.8428
p.S390L	SIDM01608	Endometrial Carcinoma	GDSC	PTPLST	DEG_SCF_FBW7_1	393:398	Mutation rewiring degron network	0.25
p.I1180T	SIDM01724	Melanoma	GDSC	SRDALPFLL	DEG_APCC_DBOX_1	1189:1197	Mutation rewiring degron network	0.0833
p.P1099S	SIDM01619	Endometrial Carcinoma	GDSC	PPLY	ITCH	1092:1095	Mutation rewiring degron network	0.2222

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons