DegronMD

Uniprot ID: A6NKB5

Source protein: Pecanex-like protein 2

Source gene: PCNX2

Class: LIG_APCC_ABBA_1

Location: 341:346

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.9448

ASA_SCORE: 96.7167

COIL: 0.816

CONS_SCORE: 0.3166

DSS_SCORE: 0.5204

HELIX: 0.1413

FCONS_SCORE: 1.0548

RIG_SCORE: 0.7211

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.R344W	SW403	large_intestine	COSMIC	LPLHQE	LIG_APCC_ABBA_1	0.8634
p.A336V	GR-ST	haematopoietic_and_lymphoid_tissue	COSMIC	LPLHQE	LIG_APCC_ABBA_1	0.1944

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
A6NKB5	Pecanex-like protein 2	LIG_APCC_ABBA_1	341:346	LPLHQE	APC,CDC20,FZR1	0.9448	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons