DegronMD

Uniprot ID: Q8IZF6

Source protein: Adhesion G-protein coupled receptor G4

Source gene: ADGRG4

Class: DEG_SCF_FBW7_1

Location: 774:781

E3 ligase: FBXW7

DEGRON score: 0.957

ASA_SCORE: 102.3

COIL: 0.916

CONS_SCORE: 0.7782

DSS_SCORE: 0.4295

HELIX: 0.013

FCONS_SCORE: 1.0206

RIG_SCORE: 0.7608

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.L790S	SK-GT-2	stomach	COSMIC	LPLTPRET	DEG_SCF_FBW7_1	0.0833
p.T781R	BC-3	haematopoietic_and_lymphoid_tissue	COSMIC	LPLTPRET	DEG_SCF_FBW7_1	0.7876

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q8IZF6	Adhesion G-protein coupled receptor G4	DEG_SCF_FBW7_1	774:781	LPLTPRET	FBXW7	0.957	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons