DegronMD

Uniprot ID: Q86TP1

Source protein: Exopolyphosphatase PRUNE1

Source gene: PRUNE1

Class: DEG_SCF_FBW7_1

Location: 407:414

E3 ligase: FBXW7

DEGRON score: 0.9949

ASA_SCORE: 59.475

COIL: 0.7998

CONS_SCORE: 0.1789

DSS_SCORE: 0.7259

HELIX: 0.1445

FCONS_SCORE: 0.9926

RIG_SCORE: 0.6235

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.P409L	SIDM01617	Endometrial Carcinoma	GDSC	LPPTPMNS	DEG_SCF_FBW7_1	0.6471

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q86TP1	Exopolyphosphatase PRUNE1	DEG_SCF_FBW7_1	407:414	LPPTPMNS	FBXW7	0.9949	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons