DegronMD

Uniprot ID: Q9NX94

Source protein: WW domain binding protein 1-like

Source gene: WBP1L

Class: LIG_APCC_ABBA_1

Location: 105:110

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.7367

ASA_SCORE: 68.9333

COIL: 0.6163

CONS_SCORE: 0.7899

DSS_SCORE: 0.2231

HELIX: 0.3488

FCONS_SCORE: 1.2136

RIG_SCORE: 0.7739

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.A113V	TCGA-A5-A0G2	UCEC	TCGA	LPPYEE	LIG_APCC_ABBA_1	0.25
p.R96Q	SIDM00966	Ovarian Carcinoma	GDSC	LPPYEE	LIG_APCC_ABBA_1	0.5278
p.R96Q	OVCA433	ovary	COSMIC	LPPYEE	LIG_APCC_ABBA_1	0.5278
p.R106Q	SIDM01118	Small Cell Lung Carcinoma	GDSC	LPPYEE	LIG_APCC_ABBA_1	0.7329
p.Y103S	ACH-000992	Head and Neck Cancer	CCLE	LPPYEE	LIG_APCC_ABBA_1	0.2778

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9NX94	WW domain binding protein 1-like	LIG_APCC_ABBA_1	105:110	LPPYEE	APC,CDC20,FZR1	0.7367	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons