DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
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Degron:
LQLYRD
Uniprot ID:
Q9P260
Source protein:
RAB11-binding protein RELCH
Source gene:
RELCH
Class:
LIG_APCC_ABBA_1
Location:
305:310
E3 ligase:
APC,CDC20,FZR1
DEGRON score:
0.7621
ASA_SCORE:
54.9
COIL:
0.1295
CONS_SCORE:
0.6318
DSS_SCORE:
0.3827
HELIX:
0.8517
FCONS_SCORE:
1.2561
RIG_SCORE:
0.8262
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with RELCH mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of LQLYRD
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q9P260
RAB11-binding protein RELCH
LIG_APCC_ABBA_1
305:310
LQLYRD
APC,CDC20,FZR1
0.7621
More...