DegronMD

Uniprot ID: Q92619

Source protein: Rho GTPase-activating protein 45 [Cleaved into: Minor histocompatibility antigen HA-1

Source gene: ARHGAP45

Class: DEG_APCC_DBOX_1

Location: 891:899

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.7301

ASA_SCORE: 48.0556

COIL: 0.3466

CONS_SCORE: 0.5433

DSS_SCORE: 0.2697

HELIX: 0.6519

FCONS_SCORE: 1.3198

RIG_SCORE: 0.7928

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.L907P	SIDM01314	Colorectal Carcinoma	GDSC	LRELLRDLP	DEG_APCC_DBOX_1	0.1111

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q92619	Rho GTPase-activating protein 45 [Cleaved into: Minor histocompatibility antigen HA-1	DEG_APCC_DBOX_1	891:899	LRELLRDLP	APC,CDC20,FZR1	0.7301	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons