DegronMD

Uniprot ID: Q96QS3

Source protein: Homeobox protein ARX

Source gene: ARX

Class: LIG_APCC_ABBA_1

Location: 410:415

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.6936

ASA_SCORE: 43.0667

COIL: 0.8648

CONS_SCORE: 0.2815

DSS_SCORE: 0.4816

HELIX: 0.0713

FCONS_SCORE: 0.7796

RIG_SCORE: 0.6785

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.A425E	DO229355	BTCA	ICGC	LSPYLD	LIG_APCC_ABBA_1	0.0556
p.P403T	DO229026	LICA	ICGC	LSPYLD	LIG_APCC_ABBA_1	0.1389
p.D415G	DO229208	THCA	ICGC	LSPYLD	LIG_APCC_ABBA_1	0.7198

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q96QS3	Homeobox protein ARX	LIG_APCC_ABBA_1	410:415	LSPYLD	APC,CDC20,FZR1	0.6936	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons