DegronMD

Uniprot ID: Q96SZ5

Source protein: 2-aminoethanethiol dioxygenase

Source gene: ADO

Class: LIG_APCC_ABBA_1

Location: 185:190

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.9901

ASA_SCORE: 72.3333

COIL: 0.7265

CONS_SCORE: 0.5416

DSS_SCORE: 0.436

HELIX: 0.0303

FCONS_SCORE: 1.1743

RIG_SCORE: 0.7472

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.A179V	SIDM02041	Colorectal Carcinoma	GDSC	LTPHRD	LIG_APCC_ABBA_1	0.1667

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q96SZ5	2-aminoethanethiol dioxygenase	LIG_APCC_ABBA_1	185:190	LTPHRD	APC,CDC20,FZR1	0.9901	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons