DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
CPH
CGC
Degron:
LTPLST
Uniprot ID:
Q9ULH7
Source protein:
Myocardin-related transcription factor B
Source gene:
MRTFB
Class:
DEG_SCF_FBW7_1
Location:
1062:1067
E3 ligase:
FBXW7
DEGRON score:
0.949
ASA_SCORE:
73.85
COIL:
0.9068
CONS_SCORE:
0.4262
DSS_SCORE:
0.4715
HELIX:
0.0265
FCONS_SCORE:
1.0136
RIG_SCORE:
0.6593
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with MRTFB mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of LTPLST
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q9ULH7
Myocardin-related transcription factor B
DEG_SCF_FBW7_1
1062:1067
LTPLST
FBXW7
0.949
More...