DegronMD

Uniprot ID: Q9BVL2

Source protein: Nucleoporin p58/p45

Source gene: NUP58

Class: DEG_SCF_FBW7_1

Location: 140:147

E3 ligase: FBXW7

DEGRON score: 0.8989

ASA_SCORE: 69.7875

COIL: 0.8648

CONS_SCORE: 0.4159

DSS_SCORE: 0.2962

HELIX: 0.053

FCONS_SCORE: 1.0952

RIG_SCORE: 0.7214

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.T151I	SIDM00771	Non-Small Cell Lung Carcinoma	GDSC	LTSTPAAS	DEG_SCF_FBW7_1	0.2222
p.T151I	NCI-H1792	lung	COSMIC	LTSTPAAS	DEG_SCF_FBW7_1	0.2222

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9BVL2	Nucleoporin p58/p45	DEG_SCF_FBW7_1	140:147	LTSTPAAS	FBXW7	0.8989	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons