DegronMD

Uniprot ID: Q9NVT9

Source protein: Armadillo repeat-containing protein 1

Source gene: ARMC1

Class: LIG_APCC_ABBA_1

Location: 221:226

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.9554

ASA_SCORE: 75.6667

COIL: 0.5037

CONS_SCORE: 0.3376

DSS_SCORE: 0.5841

HELIX: 0.0332

FCONS_SCORE: 0.7659

RIG_SCORE: 0.7515

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.T227I	TCGA-AB-2807	LAML	TCGA	LVPFQD	LIG_APCC_ABBA_1	0.3056
p.V231A	TCGA-CG-4460	STAD	TCGA	LVPFQD	LIG_APCC_ABBA_1	0.1944
p.N234T	ACH-001991	Primary	CCLE	LVPFQD	LIG_APCC_ABBA_1	0.1111

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9NVT9	Armadillo repeat-containing protein 1	LIG_APCC_ABBA_1	221:226	LVPFQD	APC,CDC20,FZR1	0.9554	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons