DegronMD

Uniprot ID: Q96RT8

Source protein: Gamma-tubulin complex component 5

Source gene: TUBGCP5

Class: DEG_SCF_FBW7_1

Location: 159:165

E3 ligase: FBXW7

DEGRON score: 0.9976

ASA_SCORE: 75.9286

COIL: 0.8456

CONS_SCORE: 0.4718

DSS_SCORE: 0.7667

HELIX: 0.1103

FCONS_SCORE: 1.102

RIG_SCORE: 0.6882

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.D173Y	TCGA-KQ-A41N	BLCA	TCGA	MDTPNWS	DEG_SCF_FBW7_1	0.1111
p.D173Y	DO223588	BLCA	ICGC	MDTPNWS	DEG_SCF_FBW7_1	0.1111
p.D173V	DO228151	PBCA	ICGC	MDTPNWS	DEG_SCF_FBW7_1	0.1111

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q96RT8	Gamma-tubulin complex component 5	DEG_SCF_FBW7_1	159:165	MDTPNWS	FBXW7	0.9976	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons