DegronMD

Uniprot ID: Q4FZB7

Source protein: Histone-lysine N-methyltransferase KMT5B

Source gene: KMT5B

Class: LIG_APCC_ABBA_1

Location: 646:651

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.9107

ASA_SCORE: 80.7167

COIL: 0.8417

CONS_SCORE: 0.2999

DSS_SCORE: 0.7237

HELIX: 0.081

FCONS_SCORE: 0.8783

RIG_SCORE: 0.5872

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Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
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Sample	Cancer	Mutation (In Degron?)	Dataset	Drug	IC50
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Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q4FZB7	Histone-lysine N-methyltransferase KMT5B	LIG_APCC_ABBA_1	646:651	MGPHSD	APC,CDC20,FZR1	0.9107	More...

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DegronMD: protein-targeted degradation, mutation and drug response to degrons