DegronMD

Uniprot ID: Q9P2P6

Source protein: StAR-related lipid transfer protein 9

Source gene: STARD9

Class: DEG_SCF_FBW7_1

Location: 3416:3422

E3 ligase: FBXW7

DEGRON score: 0.9736

ASA_SCORE: 83.3143

COIL: 0.897

CONS_SCORE: 0.5162

DSS_SCORE: 0.5808

HELIX: 0.064

FCONS_SCORE: 1.0751

RIG_SCORE: 0.6772

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.M3409L	TCGA-A5-A0VQ	UCEC	TCGA	MPTPDFT	DEG_SCF_FBW7_1	0.1389
p.M3409L	DO42113	UCEC	ICGC	MPTPDFT	DEG_SCF_FBW7_1	0.1389
p.P3410T	DO228946	LICA	ICGC	MPTPDFT	DEG_SCF_FBW7_1	0.1667
p.P3408L	ACH-000209	Bile Duct Cancer	CCLE	MPTPDFT	DEG_SCF_FBW7_1	0.1111

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9P2P6	StAR-related lipid transfer protein 9	DEG_SCF_FBW7_1	3416:3422	MPTPDFT	FBXW7	0.9736	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons