DegronMD

Uniprot ID: Q02505

Source protein: Mucin-3A

Source gene: MUC3A

Class: DEG_SCF_FBW7_1

Location: 1133:1138

E3 ligase: FBXW7

DEGRON score: 0.9886

ASA_SCORE: 98.5333

COIL: 0.9235

CONS_SCORE: 0.4534

DSS_SCORE: 0.6169

HELIX: 0.0125

FCONS_SCORE: 1

RIG_SCORE: 0.7726

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.M1133I	SIDM00967	Ovarian Carcinoma	GDSC	MTPTTT	DEG_SCF_FBW7_1	0.6507
p.T1134S	SIDM00967	Ovarian Carcinoma	GDSC	MTPTTT	DEG_SCF_FBW7_1	0.7116
p.S1124F	SIDM01059	Melanoma	GDSC	MTPTTT	DEG_SCF_FBW7_1	0.0833

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q02505	Mucin-3A	DEG_SCF_FBW7_1	1133:1138	MTPTTT	FBXW7	0.9886	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons