DegronMD

Uniprot ID: Q9H0B3

Source protein: IQ domain-containing protein N

Source gene: IQCN

Class: DEG_SCF_FBW7_1

Location: 359:366

E3 ligase: FBXW7

DEGRON score: 0.8905

ASA_SCORE: 110.325

COIL: 0.9765

CONS_SCORE: 0.5594

DSS_SCORE: 0.5247

HELIX: 0.0073

FCONS_SCORE: 1.1388

RIG_SCORE: 0.6834

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.T355S	SNU-1040	large_intestine	COSMIC	MTTTPPKT	DEG_SCF_FBW7_1	0.2222

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q9H0B3	IQ domain-containing protein N	DEG_SCF_FBW7_1	359:366	MTTTPPKT	FBXW7	0.8905	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons