DegronMD

Uniprot ID: P22674

Source protein: Cyclin-O

Source gene: CCNO

Class: DEG_SCF_FBW7_1

Location: 1:7

E3 ligase: FBXW7

DEGRON score: 0.995

ASA_SCORE: 102.7

COIL: 0.9611

CONS_SCORE: 0.2545

DSS_SCORE: 0.924

HELIX: 0.0064

FCONS_SCORE: 1.1563

RIG_SCORE: 0.6665

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.A13T	DO50374	ESAD	ICGC	MVTPCPT	DEG_SCF_FBW7_1	0.1667

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
P22674	Cyclin-O	DEG_SCF_FBW7_1	1:7	MVTPCPT	FBXW7	0.995	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons