Degron: NQPYYSNTP
Enamelin
ENAM
806:814
CBL
0.9936
95.6333
0.9481
0.7351
0.6759
0.0264
1.1755
0.6564
Degron related mutations and impact score
Mutation |
Sample |
Cancer |
Dataset |
Degron |
Degron class |
Impact score |
p.P814Q | TCGA-05-4396 | LUAD | TCGA | NQPYYSNTP | CBL_PTK | 0.7035 |
p.P814Q | DO23838 | LUAD | ICGC | NQPYYSNTP | CBL_PTK | 0.7035 |
p.Q803K | TCGA-60-2714 | LUSC | TCGA | NQPYYSNTP | CBL_PTK | 0.25 |
p.Q803K | DO26530 | LUSC | ICGC | NQPYYSNTP | CBL_PTK | 0.25 |
p.P797Q | TCGA-85-6560 | LUSC | TCGA | NQPYYSNTP | CBL_PTK | 0.0833 |
p.P797Q | DO26752 | LUSC | ICGC | NQPYYSNTP | CBL_PTK | 0.0833 |
p.G805D | TCGA-DA-A3F8 | SKCM | TCGA | NQPYYSNTP | CBL_PTK | 0.3056 |
p.G805D | DO37418 | SKCM | ICGC | NQPYYSNTP | CBL_PTK | 0.3056 |
p.P800L | TCGA-ER-A19Q | SKCM | TCGA | NQPYYSNTP | CBL_PTK | 0.1667 |
p.P800L | DO47497 | SKCM | ICGC | NQPYYSNTP | CBL_PTK | 0.1667 |
p.P808L | TCGA-EY-A1GI | UCEC | TCGA | NQPYYSNTP | CBL_PTK | 0.6471 |
p.P808L | DO41211 | UCEC | ICGC | NQPYYSNTP | CBL_PTK | 0.6471 |
p.P814L | TCGA-F4-6808 | COAD | TCGA | NQPYYSNTP | CBL_PTK | 0.7582 |
p.P814L | DO8946 | COAD | ICGC | NQPYYSNTP | CBL_PTK | 0.7582 |
p.Q818R | TCGA-FI-A2F4 | UCEC | TCGA | NQPYYSNTP | CBL_PTK | 0.2222 |
p.Q818R | DO43434 | UCEC | ICGC | NQPYYSNTP | CBL_PTK | 0.2222 |
p.P814T | TCGA-HE-7129 | KIRP | TCGA | NQPYYSNTP | CBL_PTK | 0.7031 |
p.P814T | DO20786 | KIRP | ICGC | NQPYYSNTP | CBL_PTK | 0.7031 |
p.I822M | DO230310 | COCA | ICGC | NQPYYSNTP | CBL_PTK | 0.1111 |
p.A798D | DO234256 | ESAD | ICGC | NQPYYSNTP | CBL_PTK | 0.1111 |
p.P801L | SIDM00150 | Colorectal Carcinoma | GDSC | NQPYYSNTP | CBL_PTK | 0.1944 |
p.P801L | ACH-000969 | Colon/Colorectal Cancer | CCLE | NQPYYSNTP | CBL_PTK | 0.1944 |
p.P801L | KM12 | large_intestine | COSMIC | NQPYYSNTP | CBL_PTK | 0.1944 |
Drug responses associated with ENAM mutations
Sample |
Cancer |
Mutation (In Degron?) |
Dataset |
Drug |
IC50 |
All proteins holding degron of NQPYYSNTP
Uniprot ID |
Source protein |
Degron class |
Location |
Hit |
E3 ligase |
Degron score |
Detail |
Q9NRM1 | Enamelin | CBL_PTK | 806:814 | NQPYYSNTP | CBL | 0.9936 | More... |