DegronMD

Uniprot ID: P17024

Source protein: Zinc finger protein 20

Source gene: ZNF20

Class: DEG_APCC_DBOX_1

Location: 95:103

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.9895

ASA_SCORE: 75.9111

COIL: 0.7443

CONS_SCORE: 0.5116

DSS_SCORE: 0.3527

HELIX: 0.0498

FCONS_SCORE: 1.2818

RIG_SCORE: 0.7423

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.R110H	DO234202	ESAD	ICGC	NRKTLPGIT	DEG_APCC_DBOX_1	0.1389
p.D92G	SIDM00980	Gastric Carcinoma	GDSC	NRKTLPGIT	DEG_APCC_DBOX_1	0.25
p.D92G	ACH-000948	Gastric Cancer	CCLE	NRKTLPGIT	DEG_APCC_DBOX_1	0.25
p.D92G	23132-87	stomach	COSMIC	NRKTLPGIT	DEG_APCC_DBOX_1	0.25

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
P17024	Zinc finger protein 20	DEG_APCC_DBOX_1	95:103	NRKTLPGIT	APC,CDC20,FZR1	0.9895	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons